As it passes through the various neighbourhoods, the road name changes several times, becoming Maida Vale , Kilburn High Road and Shoot-Up Hill (in Kilburn), and Cricklewood Broadway (in Cricklewood), before becoming Edgware Road once again with occasional stretches as West Hendon Broadway, and the Hyde Along the entire course, it keeps its identity as the A5 road under the Great Britain road numbering scheme The A5 proceeds beyond the ending of the Edgware Road, following the old Roman road for much of its route and terminating at Holyhead , Wales (a port for Ireland ). Among the two Edgware Road tube stations was among the sites of the 7 July bombings A bomb was detonated on a train leaving the tube station serving the Circle , District and Hammersmith & City lines and heading for Paddington tube station Six people were killed in the blast: Colin Morley, 52, Jennifer Vanda Ann Nicholson, 24, Johnathan Downey, 34, Laura Webb, 29, Michael Brewster, 52, and David Foulkes, 22. The perpetrator was the ringleader Mohammed Siddique Khan, of the 7 July bombings.

Many centuries after, the road was enhanced by the Edgware Kilburn turnpike trust in 1711, although they would happen to be rather close to the starting point of coach routes, and a number of the local hostels, some of which still exist, functioned for coaches.

The Hilton London Metropole Hotel is located in a walkable distance from both Edgware Road underground stations. The University of London has dwellings on Brown Street, east of Edgware Road, and in Sussex Gardens and Talbot Square. Along with divisions of well known chains of coffee shops and restaurants, this part of Edgware Road has several Maroush restaurants, a whisky pub and many 24-hour kebab and shawarma eateries. The Comfort Inn Edgware Road is situated in a walkable distance from Marble Arch tube station & Edgware Road.